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LC3400 Advanced High-Performance Liquid Chromatography System

The LC3400 Advanced HPLC System is designed for laboratories requiring high throughput, exceptional analytical performance, and workflow flexibility. Featuring a patented 75 MPa low-pulsation pump, flow-through needle autosampler, intelligent Smart Lab CDS software, and full detector compatibility, the system supports both routine HPLC analysis and ultra-fast separations using sub-3 μm core-shell columns.

  • Up to 75 MPa operating pressure for routine and ultra-fast HPLC analysis
  • Flow-through needle autosampler with ultra-low carryover and high injection precision
  • Supports sub-3 μm core-shell columns for faster separations and higher throughput
  • Compatible with UV, DAD, FLD, ELSD, and RID detectors
  • Smart Lab CDS with FDA 21 CFR Part 11 and GMP compliance
  • 2D-LC ready with online derivatization, dilution, and enrichment capabilities
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    product advantage

    • ScreenShot_2026-06-15_151243_648

      Upgraded High-Performance Liquid Chromatograph (HPLC)

        • Modular combination design with multiple HPLC system configurations available

        • Full range of detectors with intelligent control (UV, DAD, FLD, ELSD, RID)

        • Smart Lab workstation simplifies complex operations

        • Self-developed HPLC consumables

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    • ScreenShot_2026-06-15_151250_144

      Innovative Needle-in-Flow Autosampler

        • Needle-in-flow autosampler enables non-damaging sample injection with minimal cross-contamination

        • Supports on-line derivatization and on-line dilution functions

        • Optimized and unique design of the needle wash flow path

        • Qualitative and quantitative repeatability meets internationally leading detection standards

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    • ScreenShot_2026-06-15_142521_911

      Extended Functions to Meet Diverse User Requirements

        • Innovative check valve technology ensures excellent acetonitrile resistance

        • Valve-switchable column oven with 2 built-in positions for 250 mm HPLC columns, expandable to 4 ultra-high efficiency columns

        • Patented H.B.C algorithm effectively identifies shoulder peaks and small peaks, with wizard-guided operation and intelligent integration

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    Product Specifications

    Parameter Specification
    Product Type Advanced HPLC System
    Maximum Operating Pressure 75 MPa
    Pump Technology Patented Low-Pulsation Pump
    Injection System Flow-Through Needle Autosampler
    Column Compatibility Conventional HPLC & Sub-3 μm Core-Shell Columns
    Online Functions Derivatization, Dilution, Enrichment
    Column Oven Heating & Cooling Temperature Control
    Detector Options UV, DAD, FLD, ELSD, RID
    Software Smart Lab CDS
    Compliance FDA 21 CFR Part 11, GMP
    Advanced Functions SmartPeak Integration, H.B.C-ApexFinder
    Expandability 2D-LC Ready

    Applications

    Pharmaceutical Industry

    • API analysis

    • Impurity profiling

    • Quality control testing

    • Stability studies

    Food & Beverage Testing

    • Vitamin analysis

    • Food additives

    • Aflatoxin detection

    • Pesticide residue testing

    Environmental Monitoring

    • Organic pollutants

    • PAHs analysis

    • Water quality testing

    Petrochemical Industry

    • Aromatic hydrocarbon analysis

    • Petroleum product testing

    Research Laboratories

    • Method development

    • High-throughput screening

    • Advanced chromatography research

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    FAQ

    • Q1: Can the LC3400 support both routine HPLC and ultra-fast analysis?

    • Q2: What are the advantages of the flow-through needle autosampler?

    • Q3: Does the LC3400 support 2D-LC applications?

    • Q4: Which detectors are available?

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